ABSTRACT
Serum adenosine deaminase (ADA) levels reflect activity of stimulated T lymphocytes and its levels are raised whenever cell mediated immunity is stimulated. One hundred term normal newborns were studied to evaluate effect of BCG vaccination on serum ADA levels. Serum ADA was measured at birth and 6 weeks after BCG vaccination. Only 67 subjects came for follow up after 6 weeks. The levels were 6.69 U/litre at birth and 13.83 U/litre after 6 weeks of vaccination showing a significant rise. It is concluded that serum ADA levels can be used as a measure of cell mediated immunity after BCG vaccination.
Subject(s)
Adenosine Deaminase/blood , BCG Vaccine/administration & dosage , Case-Control Studies , Developing Countries , Evaluation Studies as Topic , Female , Humans , India , Infant, Newborn , Male , Reference Values , Tuberculosis/enzymology , VaccinationABSTRACT
The evaluation of nutritional and immunization services was undertaken in the rural ICDS block Sanwer (Madhya Pradesh) where the project is functioning from last 3 years. A door to door survey was conducted in 1993 in six Anganwadi areas in ICDS block and five randomly selected matched non ICDS rural area served as controls. There were a total of 709 children in ICDS and 500 in non ICDS block in 1-6 years age group. The difference was not statistically significant for nutritional status in the two blocks, but a remarkably better immunization status (p < 0.005) was observed in non ICDS block. The coverage for DPT (3 doses), and measles vaccination in ICDS block was 79.57% and 45.7%, respectively, while in non ICDS block it was 94.4% and 62.03%, respectively. It seems the ICDS scheme is under utilized by the community and requires immediate attention by the health authorities.
Subject(s)
Child Nutritional Physiological Phenomena , Child, Preschool , Female , Humans , Immunization/statistics & numerical data , India/epidemiology , Infant , Maternal-Child Health Centers/standards , Nutrition Disorders/epidemiology , Program Evaluation , Rural HealthSubject(s)
Asthma/complications , Bone Diseases, Developmental/complications , Child , Diagnosis, Differential , Female , Humans , MaleSubject(s)
Age Factors , Humans , Infant , Male , Tuberculosis, Meningeal/etiology , Tuberculosis, Miliary/complicationsABSTRACT
A comparison of mortality and morbidity pattern of hospital admissions of children under 14 years during 1966-68 and 1977-81 has been made. Annual admission rate has increased from 1515 to 2515, which is in proportion to the population increase of 3 lacs from 1966 to 1981. Recently more than 70% were discharged within a week as against 52% during 1966-68, indicating a faster turnover and a need for more beds. Protein energy malnutrition, infections and diarrhoea with dehydration were main killers. The pattern of mortality and morbidity has not much changed from 1966 to 81 but mortality rates at all ages have considerably declined in recent years (neonatal, post neonatal, preschool and school). Measures to decline it further have been discussed. The data should be of interest to those engaged in planning health strategies and to teachers in defining priorities in Medical education.